Fucosylated ubiquitin and orthogonally glycosylated mutant A28C: conceptually new ligands for Burkholderia ambifaria lectin (BambL)

Two orthogonal, metal free click reactions, enabled to glycosylate ubiquitin and its mutant A28C forming two protein scaffolds with high affinity for BambL, a lectin from the human pathogen Burkholderia ambifaria. A new fucoside analogue, with high affinity with BambL, firstly synthetized and co-cry...

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Detalles Bibliográficos
Autores principales: Kuhaudomlarp, Sakonwan, Cerofolini, Linda, Santarsia, Sabrina, Gillon, Emilie, Fallarini, Silvia, Lombardi, Grazia, Denis, Maxime, Giuntini, Stefano, Valori, Carolina, Fragai, Marco, Imberty, Anne, Dondoni, Alessandro, Nativi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163020/
https://www.ncbi.nlm.nih.gov/pubmed/34094460
http://dx.doi.org/10.1039/d0sc03741a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163020/
https://www.ncbi.nlm.nih.gov/pubmed/34094460
http://dx.doi.org/10.1039/d0sc03741a

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