Cargando…

Physiologically Relevant Estrogen Receptor Alpha Pathway Reporters for Single-Cell Imaging-Based Carcinogenic Hazard Assessment of Estrogenic Compounds

Estrogen receptor alpha (ERα) belongs to the nuclear hormone receptor family of ligand-inducible transcription factors and regulates gene networks in biological processes such as cell growth and proliferation. Disruption of these networks by chemical compounds with estrogenic activity can result in...

Descripción completa

Detalles Bibliográficos
Autores principales: Duijndam, Britt, Goudriaan, Annabel, van den Hoorn, Tineke, van der Stel, Wanda, Le Dévédec, Sylvia, Bouwman, Peter, van der Laan, Jan Willem, van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163057/
https://www.ncbi.nlm.nih.gov/pubmed/33769548
http://dx.doi.org/10.1093/toxsci/kfab037