Metal-chelating benzothiazole multifunctional compounds for the modulation and (64)Cu PET imaging of Aβ aggregation

While Alzheimer's Disease (AD) is the most common neurodegenerative disease, there is still a dearth of efficient therapeutic and diagnostic agents for this disorder. Reported herein are a series of new multifunctional compounds (MFCs) with appreciable affinity for amyloid aggregates that can b...

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Detalles Bibliográficos
Autores principales: Huang, Yiran, Cho, Hong-Jun, Bandara, Nilantha, Sun, Liang, Tran, Diana, Rogers, Buck E., Mirica, Liviu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163150/
https://www.ncbi.nlm.nih.gov/pubmed/34094152
http://dx.doi.org/10.1039/d0sc02641g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163150/
https://www.ncbi.nlm.nih.gov/pubmed/34094152
http://dx.doi.org/10.1039/d0sc02641g

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