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Metal-chelating benzothiazole multifunctional compounds for the modulation and (64)Cu PET imaging of Aβ aggregation
While Alzheimer's Disease (AD) is the most common neurodegenerative disease, there is still a dearth of efficient therapeutic and diagnostic agents for this disorder. Reported herein are a series of new multifunctional compounds (MFCs) with appreciable affinity for amyloid aggregates that can b...
Autores principales: | Huang, Yiran, Cho, Hong-Jun, Bandara, Nilantha, Sun, Liang, Tran, Diana, Rogers, Buck E., Mirica, Liviu M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163150/ https://www.ncbi.nlm.nih.gov/pubmed/34094152 http://dx.doi.org/10.1039/d0sc02641g |
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