Arthroscopic “Debridement and Implant Retention” With Local Administration of Exebacase (Lysin CF-301) Followed by Suppressive Tedizolid as Salvage Therapy in Elderly Patients for Relapsing Multidrug-Resistant S. epidermidis Prosthetic Knee Infection

Exebacase, a recombinantly produced lysin has recently (i) reported proof-of-concept data from a phase II study in S. aureus bacteremia and (ii) demonstrated antibiofilm activity in vitro against S. epidermidis. In patients with relapsing multidrug-resistant (MDR) S. epidermidis prosthetic knee infe...

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Detalles Bibliográficos
Autores principales: Ferry, Tristan, Batailler, Cécile, Souche, Aubin, Cassino, Cara, Chidiac, Christian, Perpoint, Thomas, le Corvaisier, Claire, Josse, Jérôme, Gaillard, Romain, Roger, Julien, Kolenda, Camille, Lustig, Sébastien, Laurent, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163228/
https://www.ncbi.nlm.nih.gov/pubmed/34055817
http://dx.doi.org/10.3389/fmed.2021.550853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163228/
https://www.ncbi.nlm.nih.gov/pubmed/34055817
http://dx.doi.org/10.3389/fmed.2021.550853

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