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A Review of the Bruton Tyrosine Kinase Inhibitors in B-Cell Malignancies

The B-cell receptor signaling pathway plays an integral role in the proliferation and survival of malignant B cells. Targeting the B-cell receptor pathway via the inhibition of Bruton tyrosine kinase (BTK) has evolved the treatment of a variety of B-cell malignancies, including chronic lymphocytic l...

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Detalles Bibliográficos
Autores principales: Moore, Donald C., Thompson, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Harborside Press LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163255/
https://www.ncbi.nlm.nih.gov/pubmed/34123480
http://dx.doi.org/10.6004/jadpro.2021.12.4.8