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Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways

Lanthipeptides are characterized by thioether crosslinks formed by post-translational modifications. The cyclization process that favors a single ring pattern over many other possible ring patterns has been the topic of much speculation. Recent studies suggest that for some systems the cyclization p...

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Detalles Bibliográficos
Autores principales: Bobeica, Silvia C., Zhu, Lingyang, Acedo, Jeella Z., Tang, Weixin, van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163290/
https://www.ncbi.nlm.nih.gov/pubmed/34094481
http://dx.doi.org/10.1039/d0sc01651a