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Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways
Lanthipeptides are characterized by thioether crosslinks formed by post-translational modifications. The cyclization process that favors a single ring pattern over many other possible ring patterns has been the topic of much speculation. Recent studies suggest that for some systems the cyclization p...
Autores principales: | Bobeica, Silvia C., Zhu, Lingyang, Acedo, Jeella Z., Tang, Weixin, van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163290/ https://www.ncbi.nlm.nih.gov/pubmed/34094481 http://dx.doi.org/10.1039/d0sc01651a |
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