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Radical condensation between benzylic alcohols and acetamides to form 3-arylpropanamides

A new radical condensation reaction is developed where benzylic alcohols and acetamides are coupled to generate 3-arylpropanamides with water as the only byproduct. The transformation is performed with potassium tert-butoxide as the only additive and gives rise to a variety of 3-arylpropanamides in...

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Detalles Bibliográficos
Autores principales: Azizi, Kobra, Madsen, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163310/
https://www.ncbi.nlm.nih.gov/pubmed/34123070
http://dx.doi.org/10.1039/d0sc02948c