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Acid-catalyzed proton exchange as a novel approach for relaxivity enhancement in Gd-HPDO3A-like complexes

A current challenge in medical diagnostics is how to obtain high MRI relaxation enhancement using Gd(III)-based contrast agents (CAs) containing the minimum concentration of Gd(III) ions. We report that in GdHPDO3A-like complexes a primary amide group located in close proximity to the coordinated hy...

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Detalles Bibliográficos
Autores principales: Leone, Loredana, Boccalon, Mariangela, Ferrauto, Giuseppe, Fábián, István, Baranyai, Zsolt, Tei, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163333/
https://www.ncbi.nlm.nih.gov/pubmed/34123071
http://dx.doi.org/10.1039/d0sc02174a