SDS-induced multi-stage unfolding of a small globular protein through different denatured states revealed by single-molecule fluorescence

Ionic surfactants such as sodium dodecyl sulfate (SDS) unfold proteins in a much more diverse yet effective way than chemical denaturants such as guanidium chloride (GdmCl). But how these unfolding processes compare on a molecular level is poorly understood. Here, we address this question by scrutin...

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Detalles Bibliográficos
Autores principales: Krainer, Georg, Hartmann, Andreas, Bogatyr, Vadim, Nielsen, Janni, Schlierf, Michael, Otzen, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163379/
https://www.ncbi.nlm.nih.gov/pubmed/34123163
http://dx.doi.org/10.1039/d0sc02100h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163379/
https://www.ncbi.nlm.nih.gov/pubmed/34123163
http://dx.doi.org/10.1039/d0sc02100h

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