TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide–alkyne cycloaddition reactions

We describe the development of TMTH-SulfoxImine (TMTHSI) as a superior click reagent. This reagent combines a great reactivity, with small size and low hydrophobicity and compares outstandingly with existing click reagents. TMTHSI can be conveniently functionalized with a variety of linkers allowing...

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Detalles Bibliográficos
Autores principales: Weterings, Jimmy, Rijcken, Cristianne J. F., Veldhuis, Harald, Meulemans, Tommi, Hadavi, Darya, Timmers, Matt, Honing, Maarten, Ippel, Hans, Liskamp, Rob M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163418/
https://www.ncbi.nlm.nih.gov/pubmed/34123155
http://dx.doi.org/10.1039/d0sc03477k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163418/
https://www.ncbi.nlm.nih.gov/pubmed/34123155
http://dx.doi.org/10.1039/d0sc03477k

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