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TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide–alkyne cycloaddition reactions
We describe the development of TMTH-SulfoxImine (TMTHSI) as a superior click reagent. This reagent combines a great reactivity, with small size and low hydrophobicity and compares outstandingly with existing click reagents. TMTHSI can be conveniently functionalized with a variety of linkers allowing...
Autores principales: | Weterings, Jimmy, Rijcken, Cristianne J. F., Veldhuis, Harald, Meulemans, Tommi, Hadavi, Darya, Timmers, Matt, Honing, Maarten, Ippel, Hans, Liskamp, Rob M. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163418/ https://www.ncbi.nlm.nih.gov/pubmed/34123155 http://dx.doi.org/10.1039/d0sc03477k |
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