A traceless linker for aliphatic amines that rapidly and quantitatively fragments after reduction

Reduction sensitive linkers (RSLs) have the potential to transform the field of drug delivery due to their ease of use and selective cleavage in intracellular environments. However, despite their compelling attributes, developing reduction sensitive self-immolative linkers for aliphatic amines has b...

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Detalles Bibliográficos
Autores principales: He, Maomao, Li, Jie, Han, Hesong, Borges, Clarissa Araujo, Neiman, Gabriel, Røise, Joachim Justad, Hadaczek, Piotr, Mendonsa, Rima, Holm, Victoria R., Wilson, Ross C., Bankiewicz, Krystof, Zhang, Yumiao, Sadlowski, Corinne M., Healy, Kevin, Riley, Lee W., Murthy, Niren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163433/
https://www.ncbi.nlm.nih.gov/pubmed/34123152
http://dx.doi.org/10.1039/d0sc00929f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163433/
https://www.ncbi.nlm.nih.gov/pubmed/34123152
http://dx.doi.org/10.1039/d0sc00929f

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