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A traceless linker for aliphatic amines that rapidly and quantitatively fragments after reduction
Reduction sensitive linkers (RSLs) have the potential to transform the field of drug delivery due to their ease of use and selective cleavage in intracellular environments. However, despite their compelling attributes, developing reduction sensitive self-immolative linkers for aliphatic amines has b...
Autores principales: | He, Maomao, Li, Jie, Han, Hesong, Borges, Clarissa Araujo, Neiman, Gabriel, Røise, Joachim Justad, Hadaczek, Piotr, Mendonsa, Rima, Holm, Victoria R., Wilson, Ross C., Bankiewicz, Krystof, Zhang, Yumiao, Sadlowski, Corinne M., Healy, Kevin, Riley, Lee W., Murthy, Niren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163433/ https://www.ncbi.nlm.nih.gov/pubmed/34123152 http://dx.doi.org/10.1039/d0sc00929f |
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