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The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties

While many protein enzymes exert their functions through multimerization, which improves both selectivity and activity, this has not yet been demonstrated for other naturally occurring catalysts. Here, we report a multimerization effect applied to catalytic DNAs (or DNAzymes) and demonstrate that th...

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Detalles Bibliográficos
Autores principales: Cheng, Yu, Cheng, Mingpan, Hao, Jingya, Jia, Guoqing, Monchaud, David, Li, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163442/
https://www.ncbi.nlm.nih.gov/pubmed/34123138
http://dx.doi.org/10.1039/d0sc02907f