Tacrolimus Protects Podocytes from Apoptosis via Downregulation of TRPC6 in Diabetic Nephropathy

Podocyte injury plays an important role in diabetic nephropathy (DN), and apoptosis is one of its mechanisms. The transient receptor potential channel 6 (TRPC6) is expressed in podocytes and mediates podocyte injury induced by high glucose levels. Tacrolimus is a novel immunosuppressive agent that i...

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Detalles Bibliográficos
Autores principales: Ma, Ruixia, Wang, Ying, Xu, Yan, Wang, Rui, Wang, Xianghua, Yu, Ning, Li, Minghui, Zhou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163546/
https://www.ncbi.nlm.nih.gov/pubmed/34095318
http://dx.doi.org/10.1155/2021/8832114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163546/
https://www.ncbi.nlm.nih.gov/pubmed/34095318
http://dx.doi.org/10.1155/2021/8832114

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