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Polymorphism of IL-1β rs16944(T/C) Associated with Serum Levels of IL-1β and Subsequent Stimulation of Extracellular Matrix Degradation Affects Intervertebral Disk Degeneration Susceptibility

PURPOSE: To investigate the association of polymorphism of IL-1β rs16944(T/C) with intervertebral disk degeneration (IDD), explore the possible mechanism and evaluate the predictive value of IL-1β for IDD. PATIENTS AND METHODS: A total of 196 consecutive patients with IDD were recruited, and 196 hea...

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Detalles Bibliográficos
Autores principales: Wang, Zhao, Song, Xiaoxia, Fang, Qingbo, Xia, Weige, Luo, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163728/
https://www.ncbi.nlm.nih.gov/pubmed/34079267
http://dx.doi.org/10.2147/TCRM.S308653