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Hypertonic stress modulates eNOS function through O-GlcNAc modification at Thr-866

O-GlcNAcylation, an energy-sensitive posttranslational modification, can regulate the activity of endothelial nitric oxide synthase (eNOS). Previous studies found that Thr866 is the key site for low-glucose-mediated regulation of eNOS O-GlcNAc. However, it is not known whether this activity function...

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Detalles Bibliográficos
Autores principales: Li, Chang, He, An, Guo, Yongzheng, Yang, Xiyang, Luo, Minghao, Cheng, Zhe, Huang, Longxiang, Xia, Yong, Luo, Suxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163736/
https://www.ncbi.nlm.nih.gov/pubmed/34050207
http://dx.doi.org/10.1038/s41598-021-90321-4