Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

Immunotherapy has reshaped the field of cancer therapeutics but the population that benefits are small in many tumor types, warranting a companion diagnostic test. While immunohistochemistry (IHC) for programmed death-ligand 1 (PD-L1) or mismatch repair (MMR) and polymerase chain reaction (PCR) for...

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Detalles Bibliográficos
Autores principales: Vathiotis, Ioannis A., Yang, Zhi, Reeves, Jason, Toki, Maria, Aung, Thazin Nwe, Wong, Pok Fai, Kluger, Harriet, Syrigos, Konstantinos N., Warren, Sarah, Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163775/
https://www.ncbi.nlm.nih.gov/pubmed/34050252
http://dx.doi.org/10.1038/s41698-021-00184-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163775/
https://www.ncbi.nlm.nih.gov/pubmed/34050252
http://dx.doi.org/10.1038/s41698-021-00184-1

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