Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer

Inositol hexakisphosphate (IP6) is an assembly cofactor for HIV-1. We report here that IP6 is also used for assembly of Rous sarcoma virus (RSV), a retrovirus from a different genus. IP6 is ~100-fold more potent at promoting RSV mature capsid protein (CA) assembly than observed for HIV-1 and removal...

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Detalles Bibliográficos
Autores principales: Obr, Martin, Ricana, Clifton L., Nikulin, Nadia, Feathers, Jon-Philip R., Klanschnig, Marco, Thader, Andreas, Johnson, Marc C., Vogt, Volker M., Schur, Florian K. M., Dick, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163826/
https://www.ncbi.nlm.nih.gov/pubmed/34050170
http://dx.doi.org/10.1038/s41467-021-23506-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163826/
https://www.ncbi.nlm.nih.gov/pubmed/34050170
http://dx.doi.org/10.1038/s41467-021-23506-0

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