Cargando…

Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer

Inositol hexakisphosphate (IP6) is an assembly cofactor for HIV-1. We report here that IP6 is also used for assembly of Rous sarcoma virus (RSV), a retrovirus from a different genus. IP6 is ~100-fold more potent at promoting RSV mature capsid protein (CA) assembly than observed for HIV-1 and removal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Obr, Martin, Ricana, Clifton L., Nikulin, Nadia, Feathers, Jon-Philip R., Klanschnig, Marco, Thader, Andreas, Johnson, Marc C., Vogt, Volker M., Schur, Florian K. M., Dick, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163826/ https://www.ncbi.nlm.nih.gov/pubmed/34050170 http://dx.doi.org/10.1038/s41467-021-23506-0

Ejemplares similares

In vitro assembly of the Rous Sarcoma Virus capsid protein into hexamer tubes at physiological temperature
por: Jaballah, Soumeya A., et al.
Publicado: (2017)

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly
por: Dick, Robert A., et al.
Publicado: (2020)

A Structural Perspective of the Role of IP6 in Immature and Mature Retroviral Assembly
por: Obr, Martin, et al.
Publicado: (2021)

Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM
por: Highland, Carolyn M., et al.
Publicado: (2023)

100 years of Rous sarcoma virus
por: Weiss, Robin A., et al.
Publicado: (2011)

A stable immature lattice packages IP(6) for HIV capsid maturation
por: Mallery, Donna L., et al.
Publicado: (2021)

IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating
por: Dick, Robert A., et al.
Publicado: (2018)

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles
por: Ricana, Clifton L., et al.
Publicado: (2020)

Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice
por: Obr, Martin, et al.
Publicado: (2023)

The Polysaccharides of Rous Sarcoma No. 1
por: Harris, R. J. C., et al.
Publicado: (1954)

Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication
por: Vana, Marcy L, et al.
Publicado: (2005)

THE IMMUNOLOGICAL RELATIONS OF THE ROUS CHICKEN SARCOMA
por: Woglom, William H.
Publicado: (1915)

Some Observations on an Ascitic Rous No. 1 Sarcoma
por: Bather, R.
Publicado: (1954)

The Preparation and Assay of the Rous No. 1 Sarcoma Agent
por: Carr, J. G., et al.
Publicado: (1951)

THE EFFECT OF ARSENIC COMPOUNDS ON THE ROUS CHICKEN SARCOMA
por: Funk, Casimir
Publicado: (1915)

Crystal structure of the Rous sarcoma virus intasome
por: Yin, Zhiqi, et al.
Publicado: (2016)

Preservation of the Agent of the Rous Sarcoma No. 1 by Freeze-Drying
por: Carr, J. G., et al.
Publicado: (1951)

The Effects of Microwaves on the Rous No. 1 Fowl Sarcoma Virus
por: Epstein, M. A., et al.
Publicado: (1951)

Molecular events in cells transformed by Rous Sarcoma virus
Publicado: (1980)

AN EXPERIMENTAL STUDY OF THE ETIOLOGY OF CHICKEN SARCOMA I (ROUS)
por: Gye, W. E., et al.
Publicado: (1929)

The road from Rous sarcoma virus to precision medicine
por: Elemento, Olivier
Publicado: (2021)

Rhesus TRIM5α Disrupts the HIV-1 Capsid at the InterHexamer Interfaces
por: Zhao, Gongpu, et al.
Publicado: (2011)

A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly
por: Renner, Nadine, et al.
Publicado: (2021)

Modulation of HIV-1 capsid multimerization by sennoside A and sennoside B via interaction with the NTD/CTD interface in capsid hexamer
por: Zhang, Da-Wei, et al.
Publicado: (2023)

Immature HIV-1 assembles from Gag dimers leaving partial hexamers at lattice edges as potential substrates for proteolytic maturation
por: Tan, Aaron, et al.
Publicado: (2021)

The Phosphomonoesterase Activity Associated with Preparations of Rous Sarcoma No. 1 Agent
por: Harris, R. J. C.
Publicado: (1954)

Indications of the Heritable Nature of Non-Susceptibility to Rous Sarcoma in Fowls
por: Greenwood, A. W., et al.
Publicado: (1948)

The Nucleic Acid of Partially Purified Rous No. 1 Sarcoma Virus
por: Bather, R.
Publicado: (1957)

Transformation of rat cerebral endothelial cells by Rous sarcoma virus
Publicado: (1983)

FURTHER STUDIES ON SPECIFIC TRANSPLANTATION ANTIGENS IN ROUS SARCOMA OF MICE
por: Jonsson, Nils, et al.
Publicado: (1965)

CELLULAR LOCALIZATION OF ROUS SARCOMA VIRUS AS STUDIED WITH FLUORESCENT ANTIBODY
por: Mellors, Robert C., et al.
Publicado: (1960)

SARCOMAS IN HAMSTERS AFTER INJECTION WITH ROUS CHICKEN TUMOR MATERIAL
por: Ahlström, C. G., et al.
Publicado: (1962)

A Broad-Spectrum Antiviral Molecule, Protoporphyrin IX, Acts as a Moderator of HIV-1 Capsid Assembly by Targeting the Capsid Hexamer
por: Zhang, Da-Wei, et al.
Publicado: (2022)

Electrostatic repulsion regulates hiv-1 capsid hexamer plasticity and assembling capacities into core-like structures
por: Brun, Sonia, et al.
Publicado: (2009)

The secrets of the stability of the HIV-1 capsid
por: Obr, Martin, et al.
Publicado: (2018)

The Deacon of Rous
por: Dana, Charles L.
Publicado: (1921)

Rouse Up
Publicado: (1873)

Growth Characteristics of the Rous No. 1 Sarcoma Grown in the Peritoneal Cavity of Chickens
por: Bather, R.
Publicado: (1954)

Multiplication of Rous No. 1 Sarcoma Agent in the Chorioallantoic Membrane of the Embryonated Egg
por: Harris, R. J. C.
Publicado: (1954)

Transformation by Rous sarcoma virus induces clathrin heavy chain phosphorylation
Publicado: (1989)

Cannot write session to /tmp/vufind_sessions/sess_r1lbbtgerhseiqktq0oeh37onp