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Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice

Mutations in the GABRG2 gene encoding the γ-aminobutyric acid (GABA) A receptor gamma 2 subunit are associated with genetic epilepsy with febrile seizures plus, febrile seizures plus, febrile seizures, and other symptoms of epilepsy. However, the mechanisms underlying Gabrg2-mediated febrile seizure...

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Detalles Bibliográficos
Autores principales: Li, Xinxiao, Guo, Shengnan, Xu, Siying, Chen, Zhangping, Wang, Lei, Ding, Jiangwei, Huo, Junming, Xiao, Lifei, He, Zhenquan, Jin, Zhe, Wang, Feng, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163876/
https://www.ncbi.nlm.nih.gov/pubmed/34050134
http://dx.doi.org/10.1038/s41419-021-03846-x