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Efficacy and Safety of Janus Kinase Inhibitors in Type I Interferon-Mediated Monogenic Autoinflammatory Disorders: A Scoping Review

IMPORTANCE: Type I interferon (IFN)-mediated monogenic autoinflammatory disorders (interferonopathies) are childhood-onset rare multisystemic diseases with limited treatment options. The Janus kinase (JAK) inhibitors are promising potential therapeutic candidates for immune-mediated chronic inflamma...

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Detalles Bibliográficos
Autores principales: Gómez-Arias, Pedro Jesús, Gómez-García, Francisco, Hernández-Parada, Jorge, Montilla-López, Ana María, Ruano, Juan, Parra-Peralbo, Esmeralda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163936/
https://www.ncbi.nlm.nih.gov/pubmed/33856640
http://dx.doi.org/10.1007/s13555-021-00517-9