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Combinatorial Therapies to Overcome BRAF/MEK Inhibitors Resistance in Melanoma Cells: An in vitro Study

BACKGROUND: Melanoma accounts for only 1% of all skin malignant tumors; however, it is the deadliest form of skin cancer. Since 2011, FDA (Food and Drug Administration) approved several novel therapeutic strategies, such as MAPK pathway targeted therapies, to treat cutaneous melanoma patients. Howev...

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Detalles Bibliográficos
Autores principales: Pópulo, Helena, Domingues, Beatriz, Sampaio, Cristina, Lopes, José Manuel, Soares, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163970/
https://www.ncbi.nlm.nih.gov/pubmed/34079392
http://dx.doi.org/10.2147/JEP.S297831