Analysis of genes regulated by DUX4 via oxidative stress reveals potential therapeutic targets for treatment of facioscapulohumeral dystrophy

Muscles of patients with facioscapulohumeral dystrophy (FSHD) are characterized by sporadic DUX4 expression and oxidative stress which is at least partially induced by DUX4 protein. Nevertheless, targeting oxidative stress with antioxidants has a limited impact on FSHD patients, and the exact role o...

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Detalles Bibliográficos
Autores principales: Karpukhina, Anna, Galkin, Ivan, Ma, Yinxing, Dib, Carla, Zinovkin, Roman, Pletjushkina, Olga, Chernyak, Boris, Popova, Ekaterina, Vassetzky, Yegor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163973/
https://www.ncbi.nlm.nih.gov/pubmed/34030118
http://dx.doi.org/10.1016/j.redox.2021.102008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163973/
https://www.ncbi.nlm.nih.gov/pubmed/34030118
http://dx.doi.org/10.1016/j.redox.2021.102008

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