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Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome in podocytes has been implicated in the initiation of glomerular inflammation during hyperhomocysteinemia (hHcy). However, the mechanism by which NLRP3 inflammasome products are released from p...

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Detalles Bibliográficos
Autores principales: Li, Guangbi, Huang, Dandan, Li, Ningjun, Ritter, Joseph K., Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163985/
https://www.ncbi.nlm.nih.gov/pubmed/34030116
http://dx.doi.org/10.1016/j.redox.2021.102013