Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion

OBJECTIVE: Transport of Ca(2+) into pancreatic β cell mitochondria facilitates nutrient-mediated insulin secretion. However, the underlying mechanism is unclear. Recent establishment of the molecular identity of the mitochondrial Ca(2+) uniporter (MCU) and associated proteins allows modification of...

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Detalles Bibliográficos
Autores principales: Vishnu, N., Hamilton, A., Bagge, A., Wernersson, A., Cowan, E., Barnard, H., Sancak, Y., Kamer, K.J., Spégel, P., Fex, M., Tengholm, A., Mootha, V.K., Nicholls, D.G., Mulder, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163986/
https://www.ncbi.nlm.nih.gov/pubmed/33932586
http://dx.doi.org/10.1016/j.molmet.2021.101239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163986/
https://www.ncbi.nlm.nih.gov/pubmed/33932586
http://dx.doi.org/10.1016/j.molmet.2021.101239

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