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Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions

The Nerve Growth Factor (NGF) neurotrophin acts in the maintenance and growth of neuronal populations. Despite the detailed knowledge of NGF’s role in neuron physiology, the structural and mechanistic determinants of NGF bioactivity modulated by essential endogenous ligands are still lacking. We pre...

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Detalles Bibliográficos
Autores principales: Paoletti, Francesca, Merzel, Franci, Cassetta, Alberto, Ogris, Iza, Covaceuszach, Sonia, Grdadolnik, Jože, Lamba, Doriano, Golič Grdadolnik, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164016/
https://www.ncbi.nlm.nih.gov/pubmed/34136093
http://dx.doi.org/10.1016/j.csbj.2021.05.009