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Tolerance to nascent protein misfolding stress requires fine-tuning of the cAMP/PKA pathway

Protein aggregation is the abnormal association of misfolded proteins into larger, often insoluble structures that can be toxic during aging and in protein aggregation-associated diseases. Previous research has established a role for the cytosolic Tsa1 peroxiredoxin in responding to protein misfoldi...

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Detalles Bibliográficos
Autores principales: Kritsiligkou, Paraskevi, Nowicki-Osuch, Karol, Carter, Zorana, Kershaw, Chris J., Creamer, Declan R., Weids, Alan J., Grant, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164027/
https://www.ncbi.nlm.nih.gov/pubmed/33894203
http://dx.doi.org/10.1016/j.jbc.2021.100690