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Double J-domain piloting of an Hsp70 substrate

Heat shock 70 kDa protein (Hsp70) chaperones play a crucial role in the biogenesis of tail-anchored proteins (TAs), starting a downstream cascade to the endoplasmic reticulum (ER) via the guided-entry-of-tail-anchored protein (GET) pathway. J-domain proteins (JDPs) are generally known to assist Hsp7...

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Detalles Bibliográficos
Autores principales: Aragonès Pedrola, Júlia, Rüdiger, Stefan G.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164044/
https://www.ncbi.nlm.nih.gov/pubmed/33930465
http://dx.doi.org/10.1016/j.jbc.2021.100717