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Phosphorylation of protein kinase Cδ Tyr311 positively regulates thromboxane generation in platelets

Platelets are key mediators of physiological hemostasis and pathological thrombosis, whose function must be carefully balanced by signaling downstream of receptors such as protease-activated receptor (PAR)4. Protein kinase C (PKC) is known to regulate various aspects of platelet function. For instan...

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Detalles Bibliográficos
Autores principales: Kostyak, John C., Mauri, Benjamin, Patel, Akruti, Dangelmaier, Carol, Reddy, Haritha, Kunapuli, Satya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164046/
https://www.ncbi.nlm.nih.gov/pubmed/33932405
http://dx.doi.org/10.1016/j.jbc.2021.100720