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Chemoprophylaxis trial designs in epidemics: insights from a systematic review of COVID-19 study registrations

BACKGROUND: Chemoprophylactics against emerging epidemic and pandemic infectious diseases offer potential for prevention but require efficacy and safety analysis before widespread use can be recommended. Chemoprophylaxis with repurposed drugs enables deployment ahead of development of novel vaccines...

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Detalles Bibliográficos
Autores principales: Manoharan, Lakshmi, Olliaro, Piero, Horby, Peter W., Watson, Conall H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164073/
https://www.ncbi.nlm.nih.gov/pubmed/34051840
http://dx.doi.org/10.1186/s13063-021-05323-4