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GM-CSF mediates immune evasion via upregulation of PD-L1 expression in extranodal natural killer/T cell lymphoma

BACKGROUND: Granulocyte-macrophage colony stimulating factor (GM-CSF) is a cytokine that is used as an immunopotentiator for anti-tumor therapies in recent years. We found that some of the extranodal natural killer/T cell lymphoma (ENKTL) patients with the treatment of hGM-CSF rapidly experienced di...

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Detalles Bibliográficos
Autores principales: Rong, Qi-xiang, Wang, Fang, Guo, Zhi-xing, Hu, Yi, An, Sai-nan, Luo, Min, Zhang, Hong, Wu, Shao-cong, Huang, Hui-qiang, Fu, Li-wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164269/
https://www.ncbi.nlm.nih.gov/pubmed/34051805
http://dx.doi.org/10.1186/s12943-021-01374-y