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Cyclin-dependent kinase 7 (CDK7) is an emerging prognostic biomarker and therapeutic target in osteosarcoma

BACKGROUND: Overexpression of cyclin-dependent kinase 7 (CDK7) is a well-known pathogenic feature of various malignancies and a sign of a more dismal prognosis. As relatively little is known about CDK7 in osteosarcoma, we elected to evaluate its expression, prognostic value, and function. METHODS: W...

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Detalles Bibliográficos
Autores principales: Ma, Hangzhan, Dean, Dylan C., Wei, Ran, Hornicek, Francis J., Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164556/
https://www.ncbi.nlm.nih.gov/pubmed/34104229
http://dx.doi.org/10.1177/1759720X21995069