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The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis
ABSTRACT: The progression of prion diseases is accompanied by the accumulation of prions in the brain. Ablation of microglia enhances prion accumulation and accelerates disease progression, suggesting that microglia play a neuroprotective role by clearing prions. However, the mechanisms underlying t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164582/ https://www.ncbi.nlm.nih.gov/pubmed/33758958 http://dx.doi.org/10.1007/s00109-021-02061-7 |