Regulation of tamoxifen sensitivity by the PLAC8/MAPK pathway axis is antagonized by curcumin-induced protein stability change

Tamoxifen resistance remains the major obstacle to the estrogen receptor positive breast cancer endocrine therapy. Placenta-specific 8 (PLAC8) has been implicated in epithelial-mesenchymal transition and tumorigenesis. However, the molecular mechanisms underlying PLAC8 function in the context of tam...

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Detalles Bibliográficos
Autores principales: Mao, Misha, Hu, Dengdi, Yang, Jingjing, Chen, Yongxia, Zhang, Xun, Shen, Jianguo, Teng, Rongyue, Zhou, Jichun, Wang, Linbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164584/
https://www.ncbi.nlm.nih.gov/pubmed/33611659
http://dx.doi.org/10.1007/s00109-021-02047-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164584/
https://www.ncbi.nlm.nih.gov/pubmed/33611659
http://dx.doi.org/10.1007/s00109-021-02047-5

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