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Corticosteroid enhances epithelial barrier function in intestinal organoids derived from patients with Crohn’s disease

ABSTRACT: Corticosteroids (CS), first-line therapeutics for Crohn’s disease (CD) with moderate or severe disease activity, were found to restore intestinal permeability in CD patients, whereas the underlying molecular events are still largely unknown. This study aimed to investigate the effect and m...

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Detalles Bibliográficos
Autores principales: Xu, Pan, Elizalde, Montserrat, Masclee, Ad, Pierik, Marieke, Jonkers, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164603/
https://www.ncbi.nlm.nih.gov/pubmed/33575854
http://dx.doi.org/10.1007/s00109-021-02045-7