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Corticosteroid enhances epithelial barrier function in intestinal organoids derived from patients with Crohn’s disease
ABSTRACT: Corticosteroids (CS), first-line therapeutics for Crohn’s disease (CD) with moderate or severe disease activity, were found to restore intestinal permeability in CD patients, whereas the underlying molecular events are still largely unknown. This study aimed to investigate the effect and m...
Autores principales: | Xu, Pan, Elizalde, Montserrat, Masclee, Ad, Pierik, Marieke, Jonkers, Daisy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164603/ https://www.ncbi.nlm.nih.gov/pubmed/33575854 http://dx.doi.org/10.1007/s00109-021-02045-7 |
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