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Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat

We discovered high Na(+) and water content in the skin of newborn Sprague–Dawley rats, which reduced ~ 2.5-fold by 7 days of age, indicating rapid changes in extracellular volume (ECV). Equivalent changes in ECV post birth were also observed in C57Bl/6 J mice, with a fourfold reduction over 7 days,...

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Detalles Bibliográficos
Autores principales: Mullins, Linda, Ivy, Jessica, Ward, Mairi, Tenstad, Olav, Wiig, Helge, Kitada, Kento, Manning, Jon, Rakova, Natalia, Muller, Dominik, Mullins, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164623/
https://www.ncbi.nlm.nih.gov/pubmed/34028587
http://dx.doi.org/10.1007/s00424-021-02582-7