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Fine-tuning neural excitation/inhibition for tailored ketamine use in treatment-resistant depression

The glutamatergic modulator ketamine has been shown to rapidly reduce depressive symptoms in patients with treatment-resistant major depressive disorder (TRD). Although its mechanisms of action are not fully understood, changes in cortical excitation/inhibition (E/I) following ketamine administratio...

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Detalles Bibliográficos
Autores principales: Fagerholm, Erik D., Leech, Robert, Williams, Steven, Zarate, Carlos A., Moran, Rosalyn J., Gilbert, Jessica R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164631/
https://www.ncbi.nlm.nih.gov/pubmed/34052834
http://dx.doi.org/10.1038/s41398-021-01442-3