ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling

Cancer stem cells (CSCs) are a major cause of tumor treatment resistance, relapse and metastasis. Cancer cells exhibit reprogrammed metabolism characterized by aerobic glycolysis, which is also critical for sustaining cancer stemness. However, regulation of cancer cell metabolism rewiring and stemne...

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Detalles Bibliográficos
Autores principales: Zhu, Tao, Zheng, Juyan, Zhuo, Wei, Pan, Pinhua, Li, Min, Zhang, Wei, Zhou, Honghao, Gao, Yang, Li, Xi, Liu, Zhaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164634/
https://www.ncbi.nlm.nih.gov/pubmed/34052833
http://dx.doi.org/10.1038/s41420-021-00508-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164634/
https://www.ncbi.nlm.nih.gov/pubmed/34052833
http://dx.doi.org/10.1038/s41420-021-00508-x

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