Effects of Polymorphisms in the Serotonin Transporter Promoter-Linked Polymorphic Region on Postthoracotomy Pain Severity

PURPOSE: Serotonin (5-HT) is highly associated with pain modulation. The human 5-HT transporter (5-HTT) gene (SLC6A4) features several polymorphisms in its promoter region (5-HTTLPR) that affect the 5-HTT expression. The S allele of 5-HTTLPR induces low 5-HT tone, and it may influence the modulation...

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Detalles Bibliográficos
Autores principales: Kimura, Aya, Yamasaki, Hiroyuki, Ishii, Haruka, Yoshida, Hisako, Shimizu, Motoko, Mori, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164694/
https://www.ncbi.nlm.nih.gov/pubmed/34079356
http://dx.doi.org/10.2147/JPR.S298685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164694/
https://www.ncbi.nlm.nih.gov/pubmed/34079356
http://dx.doi.org/10.2147/JPR.S298685

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