Downregulation of Renal MRPs Transporters in Acute Lymphoblastic Leukemia Mediated by the IL-6/STAT3/PXR Signaling Pathway

PURPOSE: Considering prior investigations on reductions of renal multidrug resistance-associated protein (MRP) 2 and 4 transporters in mice with acute lymphoblastic leukemia (ALL), we sought to characterize the underlying mechanisms responsible for IL-6/STAT3/PXR-mediated changes in the expression o...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Nie, Ai-Qing, Chen, Shang, Wang, Meng-Meng, Yin, Rui, Tang, Bo-Hao, Wu, Yue-E, Yang, Fan, Du, Bin, Shi, Hai-Yan, Yang, Xin-Mei, Hao, Guo-Xiang, Guo, Xiu-Li, Han, Qiu-Ju, Zheng, Yi, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164703/
https://www.ncbi.nlm.nih.gov/pubmed/34079330
http://dx.doi.org/10.2147/JIR.S310687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164703/
https://www.ncbi.nlm.nih.gov/pubmed/34079330
http://dx.doi.org/10.2147/JIR.S310687

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