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Downregulation of Renal MRPs Transporters in Acute Lymphoblastic Leukemia Mediated by the IL-6/STAT3/PXR Signaling Pathway

PURPOSE: Considering prior investigations on reductions of renal multidrug resistance-associated protein (MRP) 2 and 4 transporters in mice with acute lymphoblastic leukemia (ALL), we sought to characterize the underlying mechanisms responsible for IL-6/STAT3/PXR-mediated changes in the expression o...

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Detalles Bibliográficos
Autores principales:	Zhou, Yue, Nie, Ai-Qing, Chen, Shang, Wang, Meng-Meng, Yin, Rui, Tang, Bo-Hao, Wu, Yue-E, Yang, Fan, Du, Bin, Shi, Hai-Yan, Yang, Xin-Mei, Hao, Guo-Xiang, Guo, Xiu-Li, Han, Qiu-Ju, Zheng, Yi, Zhao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164703/ https://www.ncbi.nlm.nih.gov/pubmed/34079330 http://dx.doi.org/10.2147/JIR.S310687

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