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Mesenchymal Stem Cells Attenuate Renal Fibrosis via Exosomes-Mediated Delivery of microRNA Let-7i-5p Antagomir

BACKGROUND: Renal fibrosis is a chronic and progressive process affecting kidneys in chronic kidney disease (CKD). Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been shown to alleviate renal fibrosis and injury, but the mechanism of MSCs-Exo-induced renal protection remains unknown. METHOD...

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Detalles Bibliográficos
Autores principales: Jin, Juan, Qian, Fengmei, Zheng, Danna, He, Wenfang, Gong, Jianguang, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164705/
https://www.ncbi.nlm.nih.gov/pubmed/34079249
http://dx.doi.org/10.2147/IJN.S299969