Genetic analysis of sinonasal undifferentiated carcinoma discovers recurrent SWI/SNF alterations and a novel PGAP3-SRPK1 fusion gene

BACKGROUND: Sinonasal Undifferentiated Carcinoma (SNUC) is a rare and aggressive skull base tumor with poor survival and limited treatment options. To date, targeted sequencing studies have identified IDH2 and SMARCB1 as potential driver alterations, but the molecular alterations found in SMARCB1 wi...

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Detalles Bibliográficos
Autores principales: Heft Neal, Molly E., Birkeland, Andrew C., Bhangale, Apurva D., Zhai, Jingyi, Kulkarni, Aditi, Foltin, Susan K., Jewell, Brittany M., Ludwig, Megan L., Pinatti, Lisa, Jiang, Hui, McHugh, Jonathan B., Marentette, Lawence, McKean, Erin L., Brenner, J. Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164750/
https://www.ncbi.nlm.nih.gov/pubmed/34051734
http://dx.doi.org/10.1186/s12885-021-08370-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164750/
https://www.ncbi.nlm.nih.gov/pubmed/34051734
http://dx.doi.org/10.1186/s12885-021-08370-x

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