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The role of FoxP3+ regulatory T cells and IDO+ immune and tumor cells in malignant melanoma – an immunohistochemical study

BACKGROUND: FoxP3+ Regulatory T cells (Tregs) and indoleamine-2,3-dioxygenase (IDO) participate in the formation of an immunosuppressive tumor microenvironment (TME) in malignant cutaneous melanoma (CM). Recent studies have reported that IDO expression correlates with poor prognosis and greater Bres...

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Detalles Bibliográficos
Autores principales: Salmi, Satu, Lin, Anton, Hirschovits-Gerz, Benjamin, Valkonen, Mari, Aaltonen, Niina, Sironen, Reijo, Siiskonen, Hanna, Pasonen-Seppänen, Sanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164759/
https://www.ncbi.nlm.nih.gov/pubmed/34051744
http://dx.doi.org/10.1186/s12885-021-08385-4