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miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway

BACKGROUND: Stroke affects 3–4% of adults and kills numerous people each year. Recovering blood flow with minimal reperfusion-induced injury is crucial. However, the mechanisms underlying reperfusion-induced injury, particularly inflammation, are not well understood. Here, we investigated the functi...

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Detalles Bibliográficos
Autores principales: Zhou, Feng, Wang, Yu-Kai, Zhang, Cheng-Guo, Wu, Bing-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164774/
https://www.ncbi.nlm.nih.gov/pubmed/34051800
http://dx.doi.org/10.1186/s12974-021-02172-5