Senescence of donor cells impairs fat graft regeneration by suppressing adipogenesis and increasing expression of senescence-associated secretory phenotype factors

BACKGROUND: Fat grafting has been regarded as a promising approach for regenerative therapy. Given the rapidly aging population, better understanding of the effect of age on fat graft outcomes and the underlying mechanisms is urgently needed. METHODS: C57/BL6 mice [old (O, 18–20-month-old) and young...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xihang, Feng, Jingwei, Chang, Qiang, Lu, Feng, Yuan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164816/
https://www.ncbi.nlm.nih.gov/pubmed/34051860
http://dx.doi.org/10.1186/s13287-021-02383-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164816/
https://www.ncbi.nlm.nih.gov/pubmed/34051860
http://dx.doi.org/10.1186/s13287-021-02383-w

Ejemplares similares